4HLY

The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA

4HLY の概要

• エントリーDOI: 10.2210/pdb4hly/pdb
• 分子名称: K9, 5'-D(*GP*CP*GP*TP*CP*GP*AP*GP*AP*CP*GP*C)-3' (3 entities in total)
• 機能のキーワード: helix-turn-helix, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Human herpesvirus 8 (HHV-8); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 37995.77

構造登録者

Hew, K.,Venkatachalam, R. (登録日: 2012-10-17, 公開日: 2013-03-13, 最終更新日: 2024-03-20)

• 主引用文献: Hew, K.,Dahlroth, S.L.,Venkatachalam, R.,Nasertorabi, F.,Lim, B.T.,Cornvik, T.,Nordlund, P.; The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor.; Nucleic Acids Res., 41:4295-4306, 2013; PubMed: 23435230; DOI: 10.1093/nar/gkt082

実験手法

X-RAY DIFFRACTION (1.48 Å)