4HGP
Crystal Structure of 2-keto-3-deoxyoctulosonate 8-phosphate phosphohydrolase from Haemophilus influenzae in complex with transition state mimic
Summary for 4HGP
Entry DOI | 10.2210/pdb4hgp/pdb |
Related | 1k1e 4HGN 4HGO 4HGQ 4HGR |
Descriptor | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC, MAGNESIUM ION, oxido(dioxo)vanadium, ... (5 entities in total) |
Functional Keywords | rossmann fold, phosphohydroylase, hydrolase |
Biological source | Haemophilus influenzae |
Total number of polymer chains | 1 |
Total formula weight | 19816.72 |
Authors | Daughtry, K.D.,Allen, K.N. (deposition date: 2012-10-08, release date: 2013-08-21, Last modification date: 2023-09-20) |
Primary citation | Daughtry, K.D.,Huang, H.,Malashkevich, V.,Patskovsky, Y.,Liu, W.,Ramagopal, U.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Dunaway-Mariano, D.,Allen, K.N. Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis. Biochemistry, 52:5372-5386, 2013 Cited by PubMed: 23848398DOI: 10.1021/bi400659k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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