4HGO

2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphohydrolase from Bacteroides thetaiotaomicron in complex with transition state mimic

4HGO の概要

• エントリーDOI: 10.2210/pdb4hgo/pdb
• 関連するPDBエントリー: 3e8m 4HGN 4HGP 4HGQ 4HGR
• 分子名称: acylneuraminate cytidylyltransferase, MAGNESIUM ION, oxido(dioxo)vanadium, ... (5 entities in total)
• 機能のキーワード: rossmann fold, phosphohydroylase, transferase, hydrolase
• 由来する生物種: Bacteroides thetaiotaomicron
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 74477.67

構造登録者

Daughtry, K.D.,Allen, K.N. (登録日: 2012-10-08, 公開日: 2013-08-21, 最終更新日: 2023-09-20)

• 主引用文献: Daughtry, K.D.,Huang, H.,Malashkevich, V.,Patskovsky, Y.,Liu, W.,Ramagopal, U.,Sauder, J.M.,Burley, S.K.,Almo, S.C.,Dunaway-Mariano, D.,Allen, K.N.; Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis.; Biochemistry, 52:5372-5386, 2013; PubMed: 23848398; DOI: 10.1021/bi400659k

実験手法

X-RAY DIFFRACTION (2.1 Å)