4HCK
HUMAN HCK SH3 DOMAIN, NMR, 25 STRUCTURES
Summary for 4HCK
Entry DOI | 10.2210/pdb4hck/pdb |
Descriptor | HEMATOPOIETIC CELL KINASE (1 entity in total) |
Functional Keywords | sh3, protein tyrosine kinase, signal transduction, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform 1: Lysosome. Isoform 2: Cell membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle: P08631 |
Total number of polymer chains | 1 |
Total formula weight | 8240.03 |
Authors | Horita, D.A.,Baldisseri, D.M.,Zhang, W.,Altieri, A.S.,Smithgall, T.E.,Gmeiner, W.H.,Byrd, R.A. (deposition date: 1998-03-09, release date: 1998-06-17, Last modification date: 2024-05-01) |
Primary citation | Horita, D.A.,Baldisseri, D.M.,Zhang, W.,Altieri, A.S.,Smithgall, T.E.,Gmeiner, W.H.,Byrd, R.A. Solution structure of the human Hck SH3 domain and identification of its ligand binding site. J.Mol.Biol., 278:253-265, 1998 Cited by PubMed: 9571048DOI: 10.1006/jmbi.1998.1690 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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