4H88
Structure of POM1 FAB fragment complexed with mouse PrPc Fragment 120-230
Summary for 4H88
Entry DOI | 10.2210/pdb4h88/pdb |
Related | 4DGI |
Descriptor | Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ... (5 entities in total) |
Functional Keywords | c-term mouse prion protein, pom1 fab, immune system |
Biological source | Mus musculus (mouse) More |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor (By similarity): P04925 |
Total number of polymer chains | 3 |
Total formula weight | 60105.47 |
Authors | Baral, P.K.,Wieland, B.,Swayampakula, M.,James, M.N. (deposition date: 2012-09-21, release date: 2013-07-31, Last modification date: 2013-09-18) |
Primary citation | Sonati, T.,Reimann, R.R.,Falsig, J.,Baral, P.K.,O'Connor, T.,Hornemann, S.,Yaganoglu, S.,Li, B.,Herrmann, U.S.,Wieland, B.,Swayampakula, M.,Rahman, M.H.,Das, D.,Kav, N.,Riek, R.,Liberski, P.P.,James, M.N.,Aguzzi, A. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501:102-106, 2013 Cited by PubMed: 23903654DOI: 10.1038/nature12402 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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