4H3Y

Crystal structure of an asymmetric dimer of a tRNA (guanine-(N(1)-)-methyltransferase from Burkholderia phymatum bound to S-adenosyl homocystein in one half-site

Summary for 4H3Y

• Entry DOI: 10.2210/pdb4h3y/pdb
• Related: 4H3Z
• Descriptor: tRNA (guanine-N(1)-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: structural genomics, niaid, national institute of allergy and infectious diseases, seattle structural genomics center for infectious disease, ssgcid, trmd, m1g-methyltransferase, g37 methyltransferase, s-adenosyl-methionine, sam, s-adenosyl-homocysteine, sah, trna modification, transferase, proteobacteria, nitrogen fixation, food pathogen, domain swapped homodimer
• Biological source: Burkholderia phymatum
• Cellular location: Cytoplasm (Potential): B2JF31
• Total number of polymer chains: 2
• Total formula weight: 61997.72

Authors

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2012-09-14, release date: 2012-10-03, Last modification date: 2023-09-20)

• Primary citation: Baugh, L.,Gallagher, L.A.,Patrapuvich, R.,Clifton, M.C.,Gardberg, A.S.,Edwards, T.E.,Armour, B.,Begley, D.W.,Dieterich, S.H.,Dranow, D.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Staker, B.L.,Phan, I.,Gillespie, A.,Choi, R.,Nakazawa-Hewitt, S.,Nguyen, M.T.,Napuli, A.,Barrett, L.,Buchko, G.W.,Stacy, R.,Myler, P.J.,Stewart, L.J.,Manoil, C.,Van Voorhis, W.C.; Combining functional and structural genomics to sample the essential Burkholderia structome.; Plos One, 8:e53851-e53851, 2013; PubMed: 23382856; DOI: 10.1371/journal.pone.0053851

Experimental method

X-RAY DIFFRACTION (2.5 Å)