4H3D
1.95 Angstrom Crystal Structure of of Type I 3-Dehydroquinate Dehydratase (aroD) from Clostridium difficile with Covalent Modified Comenic Acid.
Summary for 4H3D
| Entry DOI | 10.2210/pdb4h3d/pdb |
| Related | 3JS3 |
| Descriptor | 3-dehydroquinate dehydratase, TRIETHYLENE GLYCOL, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
| Functional Keywords | structural genomics, center for structural genomics of infectious diseases, csgid, tim barrel, aldolase class i, 3-dehydroquinate dehydratase activity, lyase |
| Biological source | Clostridium difficile |
| Total number of polymer chains | 4 |
| Total formula weight | 118122.42 |
| Authors | Minasov, G.,Light, S.H.,Shuvalova, L.,Duban, M.-E.,Dubrovska, I.,Winsor, J.,Papazisi, L.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-09-13, release date: 2012-09-26, Last modification date: 2026-02-18) |
| Primary citation | Rosas-Lemus, M.,Dey, S.,Minasov, G.,Tan, K.,Anderson, S.M.,Brunzelle, J.,Nocadello, S.,Shabalin, I.,Filippova, E.,Halavaty, A.,Kim, Y.,Maltseva, N.,Osipiuk, J.,Minor, W.,Joachimiak, A.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.F. A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile. Microbiol Resour Announc, 12:e0050723-e0050723, 2023 Cited by PubMed Abstract: causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen. PubMed: 37747257DOI: 10.1128/MRA.00507-23 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
Download full validation report
