4H2H

Crystal structure of an enolase (mandalate racemase subgroup, target EFI-502101) from Pelagibaca bermudensis htcc2601, with bound mg and l-4-hydroxyproline betaine (betonicine)

Summary for 4H2H

• Entry DOI: 10.2210/pdb4h2h/pdb
• Related: 2PMQ
• Descriptor: Mandelate racemase/muconate lactonizing enzyme, MAGNESIUM ION, NICKEL (II) ION, ... (7 entities in total)
• Functional Keywords: enolase, mandelate racemase subgroup, enzyme function initiative, efi, structural genomics, isomerase
• Biological source: Pelagibaca bermudensis
• Total number of polymer chains: 8
• Total formula weight: 335290.08

Authors

Vetting, M.W.,Morisco, L.L.,Wasserman, S.R.,Sojitra, S.,Imker, H.J.,Gerlt, J.A.,Almo, S.C.,Enzyme Function Initiative (EFI) (deposition date: 2012-09-12, release date: 2012-10-10, Last modification date: 2023-09-20)

• Primary citation: Zhao, S.,Kumar, R.,Sakai, A.,Vetting, M.W.,Wood, B.M.,Brown, S.,Bonanno, J.B.,Hillerich, B.S.,Seidel, R.D.,Babbitt, P.C.,Almo, S.C.,Sweedler, J.V.,Gerlt, J.A.,Cronan, J.E.,Jacobson, M.P.; Discovery of new enzymes and metabolic pathways by using structure and genome context.; Nature, 502:698-702, 2013; PubMed: 24056934; DOI: 10.1038/nature12576

Experimental method

X-RAY DIFFRACTION (1.7 Å)