4H23
Cytochrome P411BM3-CIS cyclopropanation catalyst
Summary for 4H23
| Entry DOI | 10.2210/pdb4h23/pdb |
| Related | 4H24 |
| Descriptor | Cytochrome P450-BM3 variant P411BM3-Cis, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total) |
| Functional Keywords | cytochrome p450, enzymatic cyclopropanation, directed evolution, non-natural function, oxidoreductase |
| Biological source | Bacillus megaterium |
| Cellular location | Cytoplasm (By similarity): P14779 |
| Total number of polymer chains | 2 |
| Total formula weight | 108677.49 |
| Authors | Coelho, P.S.,Wang, Z.J.,Ener, M.E.,Baril, S.A.,Kannan, A.,Arnold, F.H.,Brustad, E.M. (deposition date: 2012-09-11, release date: 2013-06-26, Last modification date: 2023-09-20) |
| Primary citation | Coelho, P.S.,Wang, Z.J.,Ener, M.E.,Baril, S.A.,Kannan, A.,Arnold, F.H.,Brustad, E.M. A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo. Nat.Chem.Biol., 9:485-487, 2013 Cited by PubMed: 23792734DOI: 10.1038/nchembio.1278 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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