4H05

Crystal structure of aminoglycoside-3'-phosphotransferase of type VIII

Summary for 4H05

Entry DOI	10.2210/pdb4h05/pdb
Descriptor	Aminoglycoside-O-phosphotransferase VIII (2 entities in total)
Functional Keywords	protein kinase, atp binding, aminoglycoside phosphotransferase viii; aminoglycoside antibiotic, phosphorilation, transferase
Biological source	Streptomyces rimosus
Total number of polymer chains	2
Total formula weight	60143.66
Authors	Boyko, K.M.,Gorbacheva, M.A.,Danilenko, V.N.,Alekseeva, M.G.,Korzhenevskiy, D.A.,Dorovatovskiy, P.V.,Lipkin, A.V.,Popov, V.O. (deposition date: 2012-09-07, release date: 2014-04-09, Last modification date: 2023-09-13)
Primary citation	Boyko, K.M.,Gorbacheva, M.A.,Korzhenevskiy, D.A.,Alekseeva, M.G.,Mavletova, D.A.,Zakharevich, N.V.,Elizarov, S.M.,Rudakova, N.N.,Danilenko, V.N.,Popov, V.O. Structural characterization of the novel aminoglycoside phosphotransferase AphVIII from Streptomyces rimosus with enzymatic activity modulated by phosphorylation. Biochem.Biophys.Res.Commun., 477:595-601, 2016 Cited by PubMed: 27338640 DOI: 10.1016/j.bbrc.2016.06.097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation