4GZT

N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with oseltamivir carboxylate

4GZT の概要

• エントリーDOI: 10.2210/pdb4gzt/pdb
• 関連するPDBエントリー: 4GZO 4GZP 4GZQ 4GZS 4GZW 4GZX
• 分子名称: neuraminidase, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: beta-propella, influenza virus, neuraminidase, hemagglutinin, hemadsorption, viral infection, viral protein
• 由来する生物種: Influenza A virus
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 181424.45

構造登録者

Zhu, X.,Wilson, I.A. (登録日: 2012-09-06, 公開日: 2012-10-17, 最終更新日: 2023-09-13)

• 主引用文献: Zhu, X.,McBride, R.,Nycholat, C.M.,Yu, W.,Paulson, J.C.,Wilson, I.A.; Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors.; J.Virol., 86:13371-13383, 2012; PubMed: 23015718; DOI: 10.1128/JVI.01426-12

実験手法

X-RAY DIFFRACTION (2.19 Å)