4GZ0

Mus Musculus Tdp2-DNA Substrate Analog (5'-6-aminohexanol) Complex

Summary for 4GZ0

• Entry DOI: 10.2210/pdb4gz0/pdb
• Related: 4GYZ 4GZ1 4GZ2
• Descriptor: Tyrosyl-DNA phosphodiesterase 2, DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: protein-dna complex, dna repair, 5'-dna end processing, endonuclease/exonuclease/phosphatase domain, eep domain, 5'-dna end recognition, eep, 5'-end recognition, nuclear, hydrolase, hydrolase-dna complex, hydrolase/dna
• Biological source: Mus musculus (mouse)
• Total number of polymer chains: 12
• Total formula weight: 198651.52

Authors

Schellenberg, M.J.,Williams, R.S. (deposition date: 2012-09-05, release date: 2012-10-31, Last modification date: 2024-02-28)

• Primary citation: Schellenberg, M.J.,Appel, C.D.,Adhikari, S.,Robertson, P.D.,Ramsden, D.A.,Williams, R.S.; Mechanism of repair of 5'-topoisomerase II-DNA adducts by mammalian tyrosyl-DNA phosphodiesterase 2.; Nat.Struct.Mol.Biol., 19:1363-1371, 2012; PubMed: 23104055; DOI: 10.1038/nsmb.2418

Experimental method

X-RAY DIFFRACTION (2.113 Å)