4GVU
Lyngbyastatin 7-Porcine Pancreatic Elastase Co-crystal Structure
Summary for 4GVU
Entry DOI | 10.2210/pdb4gvu/pdb |
Related PRD ID | PRD_000776 |
Descriptor | Chymotrypsin-like elastase family member 1, Lyngbyastatin 7, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | cyanobacteria, elastase, lyngbyastatin 7, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Sus scrofa (pigs,swine,wild boar) More |
Cellular location | Secreted: P00772 |
Total number of polymer chains | 2 |
Total formula weight | 27047.29 |
Authors | Salvador, L.A.,Taori, K.,Biggs, J.S.,Jakoncic, J.,Ostrov, D.,Paul, V.J.,Luesch, H. (deposition date: 2012-08-31, release date: 2013-02-06, Last modification date: 2023-09-13) |
Primary citation | Salvador, L.A.,Taori, K.,Biggs, J.S.,Jakoncic, J.,Ostrov, D.A.,Paul, V.J.,Luesch, H. Potent elastase inhibitors from cyanobacteria: structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells. J.Med.Chem., 56:1276-1290, 2013 Cited by PubMed: 23350733DOI: 10.1021/jm3017305 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
Download full validation report