4GUH

1.95 Angstrom Crystal Structure of the Salmonella enterica 3-Dehydroquinate Dehydratase (aroD) E86A Mutant in Complex with Dehydroshikimate (Crystal Form #2)

Summary for 4GUH

Entry DOI	10.2210/pdb4guh/pdb
Related	4GUF 4GUG 4GUI 4GUJ
Descriptor	3-dehydroquinate dehydratase, (4S,5R)-4,5-dihydroxy-3-oxocyclohex-1-ene-1-carboxylic acid, NICKEL (II) ION, ... (4 entities in total)
Functional Keywords	structural genomics, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, tim barrel, lyase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Total number of polymer chains	2
Total formula weight	60489.51
Authors	Light, S.H.,Minasov, G.,Duban, M.-E.,Shuvalova, L.,Kwon, K.,Lavie, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-08-29, release date: 2012-09-12, Last modification date: 2023-09-13)
Primary citation	Light, S.H.,Anderson, W.F.,Lavie, A. Reassessing the type I dehydroquinate dehydratase catalytic triad: Kinetic and structural studies of Glu86 mutants. Protein Sci., 22:418-424, 2013 Cited by PubMed: 23341204 DOI: 10.1002/pro.2218 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation