Crystal structure of HisB from Mycobacterium tuberculosis

Summary for 4GQU

Related2f1d 1rhy 4LPF 4LOM
DescriptorImidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsmycobacterium tuberculosis, histidine biosynthesis, manganese, class- alpha and beta fold- ribosomal protein s5 domain 2-like super family-ribosomal protein s5 domain 2-like family- imidazole glycerol phoshate dehydratase domain- imidazole glycerol phosphate dehydratase, dehydratase, lyase
Biological sourceMycobacterium tuberculosis
Cellular locationCytoplasm (By similarity) P64368
Total number of polymer chains1
Total molecular weight23915.34
Ahangar, M.S.,Vyas, R.,Nasir, N.,Biswal, B.K. (deposition date: 2012-08-24, release date: 2013-08-28)
Primary citation
Ahangar, M.S.,Vyas, R.,Nasir, N.,Biswal, B.K.
Crystal structures of the native, substrate- bound and inhibited forms of Mycobacterium tuberculosis imidazole glycerol phosphate dehydratase
Acta Crystallogr.,Sect.D, 2013
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24150.5%4.6%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution