4GQN

Crystallographic structure of trimeric Riboflavin Synthase from Brucella abortus in complex with 5-Nitro-6-(D-Ribitylamino)-2,4(1H,3H) Pyrimidinedione

Summary for 4GQN

Entry DOI	10.2210/pdb4gqn/pdb
Related	1I8D 1KZL 4E0F 4FXU 4G6I
Descriptor	Riboflavin synthase subunit alpha, 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE (3 entities in total)
Functional Keywords	transferase, beta barrel, alpha + beta protein, riboflavin biosynthesis
Biological source	Brucella abortus
Total number of polymer chains	3
Total formula weight	71798.46
Authors	Serer, M.I.,Bonomi, H.R.,Guimaraes, B.G.,Rossi, R.C.,Goldbaum, F.A.,Klinke, S. (deposition date: 2012-08-23, release date: 2014-03-12, Last modification date: 2023-09-13)
Primary citation	Serer, M.I.,Bonomi, H.R.,Guimaraes, B.G.,Rossi, R.C.,Goldbaum, F.A.,Klinke, S. Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70:1419-1434, 2014 Cited by PubMed: 24816110 DOI: 10.1107/S1399004714005161 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation