4GQB

Crystal Structure of the human PRMT5:MEP50 Complex

Summary for 4GQB

Entry DOI	10.2210/pdb4gqb/pdb
Descriptor	Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ... (5 entities in total)
Functional Keywords	tim barrel, beta-propeller, methyltransferase, methylation, transferase-protein binding complex, transferase/protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	112155.91
Authors	Antonysamy, S.,Bonday, Z.,Campbell, R.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S. (deposition date: 2012-08-22, release date: 2012-10-17, Last modification date: 2018-11-21)
Primary citation	Antonysamy, S.,Bonday, Z.,Campbell, R.M.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S. Crystal structure of the human PRMT5:MEP50 complex. Proc.Natl.Acad.Sci.USA, 109:17960-17965, 2012 Cited by PubMed: 23071334 DOI: 10.1073/pnas.1209814109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation