4GQB

Crystal Structure of the human PRMT5:MEP50 Complex

4GQB の概要

• エントリーDOI: 10.2210/pdb4gqb/pdb
• 分子名称: Protein arginine N-methyltransferase 5, Methylosome protein 50, Histone H4 peptide, ... (5 entities in total)
• 機能のキーワード: tim barrel, beta-propeller, methyltransferase, methylation, transferase-protein binding complex, transferase/protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 112155.91

構造登録者

Antonysamy, S.,Bonday, Z.,Campbell, R.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S. (登録日: 2012-08-22, 公開日: 2012-10-17, 最終更新日: 2018-11-21)

• 主引用文献: Antonysamy, S.,Bonday, Z.,Campbell, R.M.,Doyle, B.,Druzina, Z.,Gheyi, T.,Han, B.,Jungheim, L.N.,Qian, Y.,Rauch, C.,Russell, M.,Sauder, J.M.,Wasserman, S.R.,Weichert, K.,Willard, F.S.,Zhang, A.,Emtage, S.; Crystal structure of the human PRMT5:MEP50 complex.; Proc.Natl.Acad.Sci.USA, 109:17960-17965, 2012; PubMed: 23071334; DOI: 10.1073/pnas.1209814109

実験手法

X-RAY DIFFRACTION (2.06 Å)