4GOS

Crystal structure of human B7-H4 IgV-like domain

4GOS の概要

• エントリーDOI: 10.2210/pdb4gos/pdb
• 分子名称: V-set domain-containing T-cell activation inhibitor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: immunoglobulin domain, glycoprotein, disulfide bond, immunity, adaptive immunity, structural genomics, psi-biology, protein structure initiative, new york structural genomics research consortium, nysgrc, immunoglobulin variable-like domain, cell surface, immune system, atoms-to-animals: the immune function network, ifn
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14633.26

構造登録者

Vigdorovich, V.,Ramagopal, U.,Bhosle, R.,Toro, R.,Nathenson, S.G.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC),Atoms-to-Animals: The Immune Function Network (IFN) (登録日: 2012-08-20, 公開日: 2012-09-12, 最終更新日: 2020-07-29)

• 主引用文献: Jeon, H.,Vigdorovich, V.,Garrett-Thomson, S.C.,Janakiram, M.,Ramagopal, U.A.,Abadi, Y.M.,Lee, J.S.,Scandiuzzi, L.,Ohaegbulam, K.C.,Chinai, J.M.,Zhao, R.,Yao, Y.,Mao, Y.,Sparano, J.A.,Almo, S.C.,Zang, X.; Structure and cancer immunotherapy of the B7 family member B7x.; Cell Rep, 9:1089-1098, 2014; PubMed: 25437562; DOI: 10.1016/j.celrep.2014.09.053

実験手法

X-RAY DIFFRACTION (1.59 Å)