4GH1

tRNA Guanine Transglycosylase in complex with morpholine substituted lin-benzohypoxanthine inhibitor

4GH1 の概要

• エントリーDOI: 10.2210/pdb4gh1/pdb
• 関連するPDBエントリー: 3S1G 3SM0 3TLL 4GG9 4GH3 4GHR 4GI4
• 分子名称: Queuine tRNA-ribosyltransferase, ZINC ION, 4-{2-[(cyclohexylmethyl)amino]ethyl}-2-{[2-(morpholin-4-yl)ethyl]amino}-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, ... (5 entities in total)
• 機能のキーワード: tim barrel, glycosyltransferase, queuosine, biosynthesis, trna processing, trna, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Zymomonas mobilis subsp. mobilis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43536.79

構造登録者

Immekus, F.,Klebe, G. (登録日: 2012-08-07, 公開日: 2013-09-04, 最終更新日: 2023-09-13)

• 主引用文献: Immekus, F.,Barandun, L.J.,Diederich, F.,Klebe, G.; Two-armed benzopurine inhibitors of TGT; To be Published,

実験手法

X-RAY DIFFRACTION (1.45 Å)