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4GGJ

Crystal structure of Zucchini from mouse (mZuc / PLD6 / MitoPLD)

Summary for 4GGJ
Entry DOI10.2210/pdb4ggj/pdb
Related1BYR 1BYS 4GGK
DescriptorMitochondrial cardiolipin hydrolase, ZINC ION (3 entities in total)
Functional Keywordspirna pathway, protein-rna interactions, pirna rnai, hkd motif ccch zinc finger, nuclease, nucleic acid binding, outer mitochondrial membrane, hydrolase
Biological sourceMus musculus (mouse)
Cellular locationMitochondrion outer membrane; Single-pass membrane protein: Q5SWZ9
Total number of polymer chains1
Total formula weight22408.24
Authors
Ipsaro, J.J.,Haase, A.D.,Hannon, G.J.,Joshua-Tor, L. (deposition date: 2012-08-06, release date: 2012-10-10, Last modification date: 2023-09-13)
Primary citationIpsaro, J.J.,Haase, A.D.,Knott, S.R.,Joshua-Tor, L.,Hannon, G.J.
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis.
Nature, 491:279-283, 2012
Cited by
PubMed: 23064227
DOI: 10.1038/nature11502
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

221051

건을2024-06-12부터공개중

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