4GAW

Crystal structure of active human granzyme H

Summary for 4GAW

• Entry DOI: 10.2210/pdb4gaw/pdb
• Related: 4GA7
• Descriptor: Granzyme H, SULFATE ION, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: serine protease, cytolysis, hydrolase, cytotoxic granules
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasmic granule: P20718
• Total number of polymer chains: 12
• Total formula weight: 304096.30

Authors

Wang, L.,Li, Q.,Wu, L.,Zhang, K.,Tong, L.,Sun, F.,Fan, Z. (deposition date: 2012-07-25, release date: 2013-01-16, Last modification date: 2023-11-08)

• Primary citation: Wang, L.,Li, Q.,Wu, L.,Liu, S.,Zhang, Y.,Yang, X.,Zhu, P.,Zhang, H.,Zhang, K.,Lou, J.,Liu, P.,Tong, L.,Sun, F.,Fan, Z.; Identification of SERPINB1 as a physiological inhibitor of human granzyme H; J.Immunol., 190:1319-1330, 2013; PubMed: 23269243; DOI: 10.4049/jimmunol.1202542

Experimental method

X-RAY DIFFRACTION (3 Å)