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4GA8

Human AKR1B10 mutant V301L complexed with NADP+ and sorbinil

Summary for 4GA8
Entry DOI10.2210/pdb4ga8/pdb
Related1ZUA
DescriptorAldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SORBINIL, ... (4 entities in total)
Functional Keywordstim barrel, aldo-keto reductase, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationLysosome : O60218
Total number of polymer chains1
Total formula weight37065.17
Authors
Cousido-Siah, A.,Ruiz Figueras, F.X.,Mitschler, A.,Podjarny, A. (deposition date: 2012-07-25, release date: 2013-08-07, Last modification date: 2023-09-13)
Primary citation

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Experimental method
X-RAY DIFFRACTION (1.942 Å)
Structure validation

227344

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