4G9Z

Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression

4G9Z の概要

• エントリーDOI: 10.2210/pdb4g9z/pdb
• 関連するPDBエントリー: 3MWP 3MWT 3MX2 3MX5
• 分子名称: RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), Nucleoprotein, ... (5 entities in total)
• 機能のキーワード: structural genomics, scottish structural proteomics facility, sspf, 3'-5'-ribonuclease, nuclease, viral protein-rna complex, viral protein/rna
• 由来する生物種: Lassa virus
• 細胞内の位置: Virion: P13699
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 26590.67

構造登録者

Jiang, X.,Huang, Q.,Wang, W.,Dong, H.,Ly, H.,Liang, Y.,Dong, C.,Scottish Structural Proteomics Facility (SSPF) (登録日: 2012-07-24, 公開日: 2013-04-03, 最終更新日: 2024-02-28)

• 主引用文献: Jiang, X.,Huang, Q.,Wang, W.,Dong, H.,Ly, H.,Liang, Y.,Dong, C.; Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.; J.Biol.Chem., 288:16949-16959, 2013; PubMed: 23615902; DOI: 10.1074/jbc.M112.420521

実験手法

X-RAY DIFFRACTION (2.03 Å)