4G8M
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist CBG-IV at 2.05A resolution
Summary for 4G8M
Entry DOI | 10.2210/pdb4g8m/pdb |
Descriptor | Glutamate receptor 2, (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclobutanecarboxylic acid, SULFATE ION, ... (6 entities in total) |
Functional Keywords | ampa receptor ligand-binding domain, glur2-s1s2j, agonist, membrane protein, membrane protein-agonist complex, membrane protein/agonist |
Biological source | Rattus norvegicus (brown rat,rat,rats) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 2 |
Total formula weight | 59752.69 |
Authors | Juknaite, L.,Frydenvang, K.,Kastrup, J.S.,Gajhede, M. (deposition date: 2012-07-23, release date: 2012-08-08, Last modification date: 2023-09-13) |
Primary citation | Juknaite, L.,Venskutonyte, R.,Assaf, Z.,Faure, S.,Gefflaut, T.,Aitken, D.J.,Nielsen, B.,Gajhede, M.,Kastrup, J.S.,Bunch, L.,Frydenvang, K.,Pickering, D.S. Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors. J.Struct.Biol., 180:39-46, 2012 Cited by PubMed: 22789682DOI: 10.1016/j.jsb.2012.07.001 PDB entries with the same primary citation |
Experimental method |
Structure validation
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