4G8M

Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist CBG-IV at 2.05A resolution

4G8M の概要

• エントリーDOI: 10.2210/pdb4g8m/pdb
• 分子名称: Glutamate receptor 2, (1S,2R)-2-[(S)-amino(carboxy)methyl]cyclobutanecarboxylic acid, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: ampa receptor ligand-binding domain, glur2-s1s2j, agonist, membrane protein, membrane protein-agonist complex, membrane protein/agonist
• 由来する生物種: Rattus norvegicus (brown rat,rat,rats); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P19491
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59752.69

構造登録者

Juknaite, L.,Frydenvang, K.,Kastrup, J.S.,Gajhede, M. (登録日: 2012-07-23, 公開日: 2012-08-08, 最終更新日: 2023-09-13)

• 主引用文献: Juknaite, L.,Venskutonyte, R.,Assaf, Z.,Faure, S.,Gefflaut, T.,Aitken, D.J.,Nielsen, B.,Gajhede, M.,Kastrup, J.S.,Bunch, L.,Frydenvang, K.,Pickering, D.S.; Pharmacological and structural characterization of conformationally restricted (S)-glutamate analogues at ionotropic glutamate receptors.; J.Struct.Biol., 180:39-46, 2012; PubMed: 22789682; DOI: 10.1016/j.jsb.2012.07.001

実験手法

X-RAY DIFFRACTION (2.05 Å)