4G7N

The Structure of the Plk4 Cryptic Polo Box Reveals Two Tandem Polo Boxes Required for Centriole Duplication

Summary for 4G7N

Entry DOI	10.2210/pdb4g7n/pdb
Descriptor	Serine/threonine-protein kinase PLK4, SULFATE ION (3 entities in total)
Functional Keywords	polo box, kinase targeting and regulation, asterless, centriole, transferase
Biological source	Drosophila melanogaster (Fruit fly)
Cellular location	Cytoplasm, cytoskeleton, centrosome, centriole: O97143
Total number of polymer chains	2
Total formula weight	51997.36
Authors	Slep, K.C.,Slevin, L.K. (deposition date: 2012-07-20, release date: 2012-10-10, Last modification date: 2012-12-12)
Primary citation	Slevin, L.K.,Nye, J.,Pinkerton, D.C.,Buster, D.W.,Rogers, G.C.,Slep, K.C. The structure of the plk4 cryptic polo box reveals two tandem polo boxes required for centriole duplication. Structure, 20:1905-1917, 2012 Cited by PubMed: 23000383 DOI: 10.1016/j.str.2012.08.025 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation