4G5Q
Structure of LGN GL4/Galphai1 complex
4G5Q の概要
エントリーDOI | 10.2210/pdb4g5q/pdb |
関連するPDBエントリー | 4G5O 4G5R 4G5S |
分子名称 | Guanine nucleotide-binding protein G(i) subunit alpha-1, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
機能のキーワード | galphai, goloco, galpha signaling, asymmetric cell division, cell cycle-signaling protein complex, cell cycle/signaling protein |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Nucleus (By similarity): P63096 Cytoplasm (By similarity): Q8VDU0 |
タンパク質・核酸の鎖数 | 8 |
化学式量合計 | 167504.22 |
構造登録者 | |
主引用文献 | Jia, M.,Li, J.,Zhu, J.,Wen, W.,Zhang, M.,Wang, W. Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins To be Published, |
実験手法 | X-RAY DIFFRACTION (2.9 Å) |
構造検証レポート
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