4G47
Structure of cytochrome P450 CYP121 in complex with 4-(1H-1,2,4-triazol-1-yl)phenol
Summary for 4G47
| Entry DOI | 10.2210/pdb4g47/pdb |
| Related | 4G44 4G45 4G46 4G48 |
| Descriptor | Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | p450, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Mycobacterium tuberculosis |
| Cellular location | Cytoplasm (By similarity): P0A514 |
| Total number of polymer chains | 1 |
| Total formula weight | 44467.76 |
| Authors | Hudson, S.A.,McLean, K.J.,Surade, S.,Yang, Y.-Q.,Leys, D.,Ciulli, A.,Munro, A.W.,Abell, C. (deposition date: 2012-07-16, release date: 2012-09-05, Last modification date: 2024-03-20) |
| Primary citation | Hudson, S.A.,McLean, K.J.,Surade, S.,Yang, Y.-Q.,Leys, D.,Ciulli, A.,Munro, A.W.,Abell, C. Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 Angew.Chem.Int.Ed.Engl., 51:9311-9316, 2012 Cited by PubMed: 22890978DOI: 10.1002/anie.201202544 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.34 Å) |
Structure validation
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