4G37

Structure of cross-linked firefly luciferase in second catalytic conformation

4G37 の概要

• エントリーDOI: 10.2210/pdb4g37/pdb
• 関連するPDBエントリー: 1LCI 2D1S 3IEP 4G36
• 分子名称: Luciferin 4-monooxygenase, 5'-O-[N-(DEHYDROLUCIFERYL)-SULFAMOYL] ADENOSINE, 4,4'-(ethylenediimino)bis[4-oxobutyrate], ... (6 entities in total)
• 機能のキーワード: anl superfamily, ligase, adenylating enzymes, luciferase, domain alternation, trapped conformation, chemical cross-linker
• 由来する生物種: Photinus pyralis (North American firefly)
• 細胞内の位置: Peroxisome: P08659
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 124213.73

構造登録者

Sundlov, J.A.,Branchini, B.R.,Gulick, A.M. (登録日: 2012-07-13, 公開日: 2012-08-15, 最終更新日: 2023-09-13)

• 主引用文献: Sundlov, J.A.,Fontaine, D.M.,Southworth, T.L.,Branchini, B.R.,Gulick, A.M.; Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.; Biochemistry, 51:6493-6495, 2012; PubMed: 22852753; DOI: 10.1021/bi300934s

実験手法

X-RAY DIFFRACTION (2.396 Å)