4FXF
Structure of M2 pyruvate kinase in complex with phenylalanine
Summary for 4FXF
| Entry DOI | 10.2210/pdb4fxf/pdb |
| Related | 1BJF 4FXJ |
| Descriptor | Pyruvate kinase isozymes M1/M2, OXALATE ION, POTASSIUM ION, ... (7 entities in total) |
| Functional Keywords | tim barrel, transferase, atp binding |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 243685.94 |
| Authors | Walkinshaw, M.D.,Morgan, H.P. (deposition date: 2012-07-03, release date: 2013-03-27, Last modification date: 2023-09-13) |
| Primary citation | Morgan, H.P.,O'Reilly, F.J.,Wear, M.A.,O'Neill, J.R.,Fothergill-Gilmore, L.A.,Hupp, T.,Walkinshaw, M.D. M2 pyruvate kinase provides a mechanism for nutrient sensing and regulation of cell proliferation. Proc.Natl.Acad.Sci.USA, 110:5881-5886, 2013 Cited by PubMed: 23530218DOI: 10.1073/pnas.1217157110 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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