4FU0

Crystal Structure of VanG D-Ala:D-Ser Ligase from Enterococcus faecalis

Summary for 4FU0

• Entry DOI: 10.2210/pdb4fu0/pdb
• Descriptor: D-alanine--D-alanine ligase 7, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: vancomycin resistance, peptidoglycan synthesis, d-ala:d-ser ligase, atp-grasp domain, ligase
• Biological source: Enterococcus faecalis
• Cellular location: Cytoplasm (By similarity): Q6WRY5
• Total number of polymer chains: 2
• Total formula weight: 81403.71

Authors

Meziane-Cherif, D.,Saul, F.A.,Haouz, A.,Courvalin, P. (deposition date: 2012-06-28, release date: 2012-09-19, Last modification date: 2023-11-08)

• Primary citation: Meziane-Cherif, D.,Saul, F.A.,Haouz, A.,Courvalin, P.; Structural and functional characterization of VanG D-Ala:D-Ser ligase associated with vancomycin resistance in Enterococcus faecalis; J.Biol.Chem., 287:37583-37592, 2012; PubMed: 22969085; DOI: 10.1074/jbc.M112.405522

Experimental method

X-RAY DIFFRACTION (2.35 Å)