4FOL

S-formylglutathione hydrolase Variant H160I

Summary for 4FOL

Entry DOI	10.2210/pdb4fol/pdb
Related	1PV1 3C6B 4FLM
Descriptor	S-formylglutathione hydrolase (2 entities in total)
Functional Keywords	d-type esterase, oxidation sensor motif, esterase activity activation, esterase activity inhibition, hydrolase
Biological source	Saccharomyces cerevisiae (yeast)
Cellular location	Cytoplasm: P40363
Total number of polymer chains	4
Total formula weight	135808.64
Authors	Legler, P.M.,Millard, C.B. (deposition date: 2012-06-20, release date: 2012-09-05, Last modification date: 2023-09-13)
Primary citation	Legler, P.M.,Leary, D.H.,Hervey, W.J.,Millard, C.B. A role for His-160 in peroxide inhibition of S. cerevisiae S-formylglutathione hydrolase: Evidence for an oxidation sensitive motif. Arch.Biochem.Biophys., 528:7-20, 2012 Cited by PubMed: 22906720 DOI: 10.1016/j.abb.2012.08.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation