4FID

Crystal structure of a heterotrimeric G-Protein subunit from entamoeba histolytica, EHG-ALPHA-1

4FID の概要

• エントリーDOI: 10.2210/pdb4fid/pdb
• 分子名称: G protein alpha subunit, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
• 機能のキーワード: ras-like domain, all-helical domain, gtp binding, nucleotide binding, signaling protein, transducer, lipoprotein, reductive methylation
• 由来する生物種: Entamoeba histolytica
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78178.31

構造登録者

Bosch, D.E.,Kimple, A.J.,Muller, R.E.,Gigure, P.M.,Willard, F.S.,Machius, M.,Temple, B.R.,Siderovski, D.P. (登録日: 2012-06-08, 公開日: 2012-11-28, 最終更新日: 2013-06-26)

• 主引用文献: Bosch, D.E.,Kimple, A.J.,Muller, R.E.,Giguere, P.M.,Machius, M.,Willard, F.S.,Temple, B.R.,Siderovski, D.P.; Heterotrimeric G-protein Signaling Is Critical to Pathogenic Processes in Entamoeba histolytica.; Plos Pathog., 8:e1003040-e1003040, 2012; PubMed: 23166501; DOI: 10.1371/journal.ppat.1003040

実験手法

X-RAY DIFFRACTION (2.62 Å)