4FFY
Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007.
Summary for 4FFY
Entry DOI | 10.2210/pdb4ffy/pdb |
Related | 3IRC 4FFZ |
Descriptor | DENV1-E111 single chain variable fragment (light chain), DENV1-E111 single chain variable fragment (heavy chain), envelope glycoprotein, ... (7 entities in total) |
Functional Keywords | viral envelope proteins, structural genomics, antibody epitopes, flavivirus, dengue virus, niaid, national institute of allergy and infectious diseases, center for structural genomics of infectious diseases, csgid, immune system, immune system-viral protein complex, immune system/viral protein |
Biological source | Mus musculus More |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9J7C6 |
Total number of polymer chains | 3 |
Total formula weight | 40230.40 |
Authors | Austin, S.K.,Nelson, C.A.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-06-01, release date: 2012-06-20, Last modification date: 2012-10-31) |
Primary citation | Austin, S.K.,Dowd, K.A.,Shrestha, B.,Nelson, C.A.,Edeling, M.A.,Johnson, S.,Pierson, T.C.,Diamond, M.S.,Fremont, D.H. Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope. Plos Pathog., 8:e1002930-e1002930, 2012 Cited by PubMed: 23055922DOI: 10.1371/journal.ppat.1002930 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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