4FBX

Complex structure of human protein kinase CK2 catalytic subunit crystallized in the presence of a bisubstrate inhibitor

Summary for 4FBX

Entry DOI	10.2210/pdb4fbx/pdb
Related	1JWH 1LP4 3BQC 3NSZ 3OFM
Related PRD ID	PRD_000870
Descriptor	Casein kinase II subunit alpha, bisubstrate inhibitor, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	protein kinase fold, protein phosphorylation, bisubstrate inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	41465.41
Authors	Enkvist, E.,Viht, K.,Bischoff, N.,Vahter, J.,Saaver, S.,Raidaru, G.,Issinger, O.-G.,Niefind, K.,Uri, A. (deposition date: 2012-05-23, release date: 2012-10-17, Last modification date: 2024-02-28)
Primary citation	Enkvist, E.,Viht, K.,Bischoff, N.,Vahter, J.,Saaver, S.,Raidaru, G.,Issinger, O.G.,Niefind, K.,Uri, A. A subnanomolar fluorescent probe for protein kinase CK2 interaction studies. Org.Biomol.Chem., 10:8645-8653, 2012 Cited by PubMed: 23032938 DOI: 10.1039/c2ob26022k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation