4FBQ

Crystal structure of a covalently fused Nbs1-Mre11 complex with two manganese ions per active site

4FBQ の概要

• エントリーDOI: 10.2210/pdb4fbq/pdb
• 関連するPDBエントリー: 4fbk 4FBW 4FCX
• 分子名称: DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION (3 entities in total)
• 機能のキーワード: dna double-strand break repair, nuclease, hydrolase, protein binding
• 由来する生物種: Schizosaccharomyces pombe (Fission yeast); 詳細
• 細胞内の位置: Nucleus : Q09683
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 106923.58

構造登録者

Schiller, C.B.,Lammens, K.,Hopfner, K.P. (登録日: 2012-05-23, 公開日: 2012-06-20, 最終更新日: 2024-02-28)

• 主引用文献: Schiller, C.B.,Lammens, K.,Guerini, I.,Coordes, B.,Feldmann, H.,Schlauderer, F.,Mockel, C.,Schele, A.,Strasser, K.,Jackson, S.P.,Hopfner, K.P.; Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling.; Nat.Struct.Mol.Biol., 19:693-700, 2012; PubMed: 22705791; DOI: 10.1038/nsmb.2323

実験手法

X-RAY DIFFRACTION (2.5 Å)