4FAK

Crystal Structure of OrfX in Complex with S-Adenosylmethionine

Summary for 4FAK

Entry DOI	10.2210/pdb4fak/pdb
Descriptor	Ribosomal RNA large subunit methyltransferase H, S-ADENOSYLMETHIONINE, TETRAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	alpha/beta methyltransferase rossmann fold, rrna methylation, adomet, rrna, transferase, ribosomal protein
Biological source	Staphylococcus aureus
Cellular location	Cytoplasm (Potential): P0C1V0
Total number of polymer chains	1
Total formula weight	19440.45
Authors	Safo, M.K.,Musayev, F.N.,Boundy, S.,Archer, G.L.,Rife, J.P.,O'Farrell, H.C. (deposition date: 2012-05-22, release date: 2012-06-06, Last modification date: 2023-09-13)
Primary citation	Boundy, S.,Safo, M.K.,Wang, L.,Musayev, F.N.,O'Farrell, H.C.,Rife, J.P.,Archer, G.L. Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site. J.Biol.Chem., 288:132-140, 2013 Cited by PubMed: 23150671 DOI: 10.1074/jbc.M112.385138 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation