4F9C

Human CDC7 kinase in complex with DBF4 and XL413

4F9C の概要

• エントリーDOI: 10.2210/pdb4f9c/pdb
• 関連するPDBエントリー: 4F99 4F9A 4F9B
• 分子名称: Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, ... (5 entities in total)
• 機能のキーワード: ser/thr protein kinase, transferase, phosphorylation, cell cycle, cell division, mitosis, s phase, serine/threonine-protein kinase, dbf4-dependent kinase, ddk, atp-binding, nucleotide-binding, zinc-binding, nucleus, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: O00311 Q9UBU7
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57912.37

構造登録者

Hughes, S.,Cherepanov, P. (登録日: 2012-05-18, 公開日: 2012-10-31, 最終更新日: 2024-02-28)

• 主引用文献: Hughes, S.,Elustondo, F.,Di Fonzo, A.,Leroux, F.G.,Wong, A.C.,Snijders, A.P.,Matthews, S.J.,Cherepanov, P.; Crystal structure of human CDC7 kinase in complex with its activator DBF4.; Nat.Struct.Mol.Biol., 19:1101-1107, 2012; PubMed: 23064647; DOI: 10.1038/nsmb.2404

実験手法

X-RAY DIFFRACTION (2.08 Å)