4F9C
Human CDC7 kinase in complex with DBF4 and XL413
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cell division cycle 7-related protein kinase | polymer | 361 | 40633.8 | 1 | UniProt (O00311) Pfam (PF00069) In PDB | Homo sapiens (human) | CDC7-related kinase, HsCdc7, huCdc7 |
2 | B | Protein DBF4 homolog A | polymer | 144 | 16923.4 | 1 | UniProt (Q9UBU7) Pfam (PF07535) In PDB | Homo sapiens (human) | Activator of S phase kinase, Chiffon homolog A, DBF4-type zinc finger-containing protein 1 |
3 | A | 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one | non-polymer | 289.7 | 1 | Chemie (0SX) | |||
4 | B | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
A: 37 - 359 (UniProt: O00311)
A: 360 - 529 (UniProt: O00311)
A: 530 - 574 (UniProt: O00311)
B: 210 - 350 (UniProt: Q9UBU7)
PDB | External Database | Details |
---|---|---|
Met 36 | - | expression tag |
A: 530 - 574 (UniProt: O00311)
B: 210 - 350 (UniProt: Q9UBU7)
PDB | External Database | Details |
---|---|---|
Gly 207 | - | expression tag |
Pro 208 | - | expression tag |
Gly 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57557.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 355.1 | |
All* | Total formula weight | 57912.4 |