4F8H

X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel

Summary for 4F8H

• Entry DOI: 10.2210/pdb4f8h/pdb
• Descriptor: Proton-gated ion channel, (R)-ketamine, tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: ketamine, pentameric ligand-gated ion channel, ion channel, anesthetics, transport protein
• Biological source: Gloeobacter violaceus
• Total number of polymer chains: 5
• Total formula weight: 193710.70

Authors

Pan, J.J.,Chen, Q.,Willenbring, D.,Kong, X.P.,Cohen, A.,Xu, Y.,Tang, P. (deposition date: 2012-05-17, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Pan, J.,Chen, Q.,Willenbring, D.,Mowrey, D.,Kong, X.P.,Cohen, A.,Divito, C.B.,Xu, Y.,Tang, P.; Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.; Structure, 20:1463-1469, 2012; PubMed: 22958642; DOI: 10.1016/j.str.2012.08.009

Experimental method

X-RAY DIFFRACTION (2.99 Å)