4F8H

X-ray Structure of the Anesthetic Ketamine Bound to the GLIC Pentameric Ligand-gated Ion Channel

4F8H の概要

• エントリーDOI: 10.2210/pdb4f8h/pdb
• 分子名称: Proton-gated ion channel, (R)-ketamine, tetradecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, ... (5 entities in total)
• 機能のキーワード: ketamine, pentameric ligand-gated ion channel, ion channel, anesthetics, transport protein
• 由来する生物種: Gloeobacter violaceus
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 193710.70

構造登録者

Pan, J.J.,Chen, Q.,Willenbring, D.,Kong, X.P.,Cohen, A.,Xu, Y.,Tang, P. (登録日: 2012-05-17, 公開日: 2012-08-29, 最終更新日: 2023-09-13)

• 主引用文献: Pan, J.,Chen, Q.,Willenbring, D.,Mowrey, D.,Kong, X.P.,Cohen, A.,Divito, C.B.,Xu, Y.,Tang, P.; Structure of the Pentameric Ligand-Gated Ion Channel GLIC Bound with Anesthetic Ketamine.; Structure, 20:1463-1469, 2012; PubMed: 22958642; DOI: 10.1016/j.str.2012.08.009

実験手法

X-RAY DIFFRACTION (2.99 Å)