4F8B
Crystal Structure of the Covalent Thioimide Intermediate of Unimodular Nitrile Reductase QueF
Summary for 4F8B
Entry DOI | 10.2210/pdb4f8b/pdb |
Related | 4FGC |
Descriptor | NADPH-dependent 7-cyano-7-deazaguanine reductase, 2-amino-5-[(Z)-iminomethyl]-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | beta barrel, protein thioimide complex, pterin binding fold, tunnel fold, trna modification enzyme, 7-cyano-7-deazaguanine, nadph, oxidoreductase |
Biological source | Bacillus subtilis subsp. subtilis |
Cellular location | Cytoplasm : O31678 |
Total number of polymer chains | 5 |
Total formula weight | 98240.05 |
Authors | Stec, B.,Swairjo, M.A. (deposition date: 2012-05-17, release date: 2012-07-11, Last modification date: 2023-09-13) |
Primary citation | Chikwana, V.M.,Stec, B.,Lee, B.W.,de Crecy-Lagard, V.,Iwata-Reuyl, D.,Swairjo, M.A. Structural basis of biological nitrile reduction. J.Biol.Chem., 287:30560-30570, 2012 Cited by PubMed: 22787148DOI: 10.1074/jbc.M112.388538 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.502 Å) |
Structure validation
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