4F7H
The crystal structure of kindlin-2 pleckstrin homology domain in free form
Summary for 4F7H
Entry DOI | 10.2210/pdb4f7h/pdb |
Related | 2LKO |
Descriptor | Fermitin family homolog 2, S,R MESO-TARTARIC ACID (3 entities in total) |
Functional Keywords | beta-barrel, membrane binding, integrin activation, cytoplasmic membrane, cell adhesion |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cell cortex: Q96AC1 |
Total number of polymer chains | 1 |
Total formula weight | 19733.31 |
Authors | |
Primary citation | Liu, Y.,Zhu, Y.,Ye, S.,Zhang, R. Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3:434-440, 2012 Cited by PubMed: 22653426DOI: 10.1007/s13238-012-2046-1 PDB entries with the same primary citation |
Experimental method |
Structure validation
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