4F7H

The crystal structure of kindlin-2 pleckstrin homology domain in free form

4F7H の概要

関連するPDBエントリー2LKO
分子名称Fermitin family homolog 2, S,R MESO-TARTARIC ACID (3 entities in total)
機能のキーワードbeta-barrel, membrane binding, integrin activation, cytoplasmic membrane, cell adhesion
由来する生物種Homo sapiens (human)
細胞内の位置Cytoplasm, cell cortex Q96AC1
ポリマー鎖数1
分子量合計19733.31
構造登録者
Liu, Y.,Zhu, Y.,Qin, J.,Ye, S.,Zhang, R. (登録日: 2012-05-16, 公開日: 2012-06-13, 最終更新日: 2012-07-18)
主引用文献
Liu, Y.,Zhu, Y.,Ye, S.,Zhang, R.
Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation.
Protein Cell, 3:434-440, 2012
PubMed: 22653426 (主引用文献が同じPDBエントリー)
DOI: 10.1007/s13238-012-2046-1
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.9 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.220503.3%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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