4F7G

Crystal structure of talin autoinhibition complex

Summary for 4F7G

• Entry DOI: 10.2210/pdb4f7g/pdb
• Descriptor: Talin-1 (3 entities in total)
• Functional Keywords: alpha-helix bundle, integrin activation, cell adhesion
• Biological source: Mus musculus (mouse); More
• Cellular location: Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side (By similarity): P26039 P26039
• Total number of polymer chains: 2
• Total formula weight: 48472.89

Authors

Song, X.,Qin, J.,Ye, S.,Zhang, R. (deposition date: 2012-05-16, release date: 2012-07-04, Last modification date: 2024-02-28)

• Primary citation: Song, X.,Yang, J.,Hirbawi, J.,Ye, S.,Perera, H.D.,Goksoy, E.,Dwivedi, P.,Plow, E.F.,Zhang, R.,Qin, J.; A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.; Cell Res., 22:1533-1545, 2012; PubMed: 22710802; DOI: 10.1038/cr.2012.97

Experimental method

X-RAY DIFFRACTION (2.05 Å)