4F52

Structure of a Glomulin-RBX1-CUL1 complex

Summary for 4F52

Entry DOI	10.2210/pdb4f52/pdb
Descriptor	Cullin-1, E3 ubiquitin-protein ligase RBX1, Glomulin, ... (4 entities in total)
Functional Keywords	cullin-ring e3 ligase, inhibitor, cell cycle-ligase-signaling protein complex, cell cycle/ligase/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P62877
Total number of polymer chains	6
Total formula weight	226362.20
Authors	Duda, D.M.,Olszewski, J.L.,Schulman, B.A. (deposition date: 2012-05-11, release date: 2012-09-19, Last modification date: 2024-02-28)
Primary citation	Duda, D.M.,Olszewski, J.L.,Tron, A.E.,Hammel, M.,Lambert, L.J.,Waddell, M.B.,Mittag, T.,Decaprio, J.A.,Schulman, B.A. Structure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding Surface. Mol.Cell, 47:371-382, 2012 Cited by PubMed: 22748924 DOI: 10.1016/j.molcel.2012.05.044 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation