4F4V

Human Insulin

Summary for 4F4V

Related3I3Z 4EWW 4EWX 4EWZ 4EX0 4EX1 4EXX 4EY1 4EY9 4EYD 4EYN 4EYP 4F0N 4F0O 4F1A 4F1B 4F1C 4F1D 4F1F 4F1G 4F4T 4F51
DescriptorInsulin A chain, Insulin B chain, ZINC ION, ... (5 entities in total)
Functional Keywordspancreatic hormone, hormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11837.03
Authors
Favero-Retto, M.P.,Palmieri, L.C.,Lima, L.M.T.R. (deposition date: 2012-05-11, release date: 2013-05-15, Last modification date: 2013-12-18)
Primary citation
Favero-Retto, M.P.,Palmieri, L.C.,Souza, T.A.,Almeida, F.C.,Lima, L.M.
Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85:1112-1121, 2013
PubMed: 23692694 (PDB entries with the same primary citation)
DOI: 10.1016/j.ejpb.2013.05.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.637 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2631502.2%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report