Structure of the Haptoglobin-Haemoglobin Complex

Summary for 4F4O

DescriptorHemoglobin subunit alpha, Hemoglobin subunit beta, Haptoglobin, ... (7 entities in total)
Functional Keywordsglobin fold, serine protease fold, complement control protein, haemoglobin scavenging, oxygen storage-transport complex, oxygen transport-transport protein complex, oxygen transport/transport protein
Biological sourceSus scrofa (pigs,swine,wild boar)
Cellular locationSecreted (By similarity) Q8SPS7
Total number of polymer chains12
Total molecular weight288435.36
Andersen, C.B.F.,Torvund-Jensen, M.,Nielsen, M.J.,Oliveira, C.L.P.,Hersleth, H.P.,Andersen, N.H.,Pedersen, J.S.,Andersen, G.R.,Moestrup, S.K. (deposition date: 2012-05-11, release date: 2012-08-29, Last modification date: 2012-09-26)
Primary citation
Andersen, C.B.,Torvund-Jensen, M.,Nielsen, M.J.,de Oliveira, C.L.,Hersleth, H.P.,Andersen, N.H.,Pedersen, J.S.,Andersen, G.R.,Moestrup, S.K.
Structure of the haptoglobin-haemoglobin complex.
Nature, 489:456-459, 2012
PubMed: 22922649 (PDB entries with the same primary citation)
DOI: 10.1038/nature11369
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.227100.3%14.7%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution