4F4C

The Crystal Structure of the Multi-Drug Transporter

Summary for 4F4C

Entry DOI	10.2210/pdb4f4c/pdb
Descriptor	Multidrug resistance protein pgp-1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside (3 entities in total)
Functional Keywords	abc transporter, atpase, multi-drug transporter, exporter, atp binding, hydrolase, protein transport
Biological source	Caenorhabditis elegans (nematode)
Total number of polymer chains	1
Total formula weight	146991.33
Authors	Jin, M.S.,Oldham, M.L.,Zhang, Q.,Chen, J. (deposition date: 2012-05-10, release date: 2012-09-26, Last modification date: 2023-09-13)
Primary citation	Jin, M.S.,Oldham, M.L.,Zhang, Q.,Chen, J. Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans. Nature, 490:566-569, 2012 Cited by PubMed: 23000902 DOI: 10.1038/nature11448 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation